Abstract

MONTIEL-JAROLIN, Dora Elizabeth et al. Report of two cases of neuro-paracoccidiomycosis. Rev. cient. cienc. salud [online]. 2023, vol.5, e5202.  Epub Mar 01, 2023. ISSN 2664-2891.  https://doi.org/10.53732/rccsalud/2023.e5202.

Paracoccidioidomycosis is the most common systemic mycosis in Latin America. Central nervous system (CNS) involvement is described in 10-27%. The objective is to present two male patients with neuroparacoccidioidomycosis admitted to the Department of Internal Medicine of the National Hospital, one in 2017 and the other in 2021. Both patients presented neurological symptoms with improvement of the lesions with amphotericin B. The granulomas brain cells of PCM may have pseudotumor behavior. Regression of the lesions was complete with amphotericin B and trimethoprim sulfamethoxazole in the first case and amphotericin B and itraconazole in the second case.

Keywords : paracoccidioidomycosis; invasive fungal infections; brain abscess.

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