Resumen

GONZALEZ, Francisco Javier; SOSA ECKERTH, Herrman Roberto; MOREIRA PARRA, José Antonio  y  BARRAIL HELLMAN, Albert Rafael. Primary progressive multiple sclerosis in a young adult. Rev. virtual Soc. Parag. Med. Int. [online]. 2025, vol.12, n.1, e12142515.  Epub 23-Ago-2025. ISSN 2312-3893.  https://doi.org/10.18004/rvspmi/2312-3893/2025.e12142515.

Multiple sclerosis is a condition known as the “disease with a thousand faces” due to the wide variety of clinical presentations it exhibits throughout its course. It is a disease that affects the central nervous system, causing demyelination of different areas of the nervous system, with symptoms depending on the specific area affected.

We present the clinical case of a 35-year-old male patient who was diagnosed with primary progressive MS after meeting the current diagnostic criteria. Despite treatment with natalizumab, indicated under the initial diagnosis of MS, the patient presented a gradual progression of his neurological deficit, which retrospectively allowed the identification of a primary progressive form of the disease.

The aim is to emphasize the need for physicians who are not specialists in clinical neurology to be able to recognize the neurological condition for correct referral to a trained professional, timely diagnosis, and early treatment.

Palabras clave : multiple sclerosis; primary progressive multiple sclerosis; oligoclonal bands; demyelinating diseases.

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