Resumen

VALDEZ MARTINEZ, Valeria Rosalba  y  ACOSTA COLMAN, Karina Raquel. Pituitary apoplexy: sudden manifestation of a silent macroadenoma. Rev. virtual Soc. Parag. Med. Int. [online]. 2025, vol.12, n.1, e12142511.  Epub 26-Jun-2025. ISSN 2312-3893.  https://doi.org/10.18004/rvspmi/2312-3893/2025.e12142511.

Pituitary apoplexy is a rare neuroendocrine emergency, usually caused by hemorrhage or ischemia in a previously existing pituitary adenoma. This report presents the case of a 69-year-old male patient who, after being diagnosed with a silent pituitary macroadenoma without symptoms at onset, suddenly presented with a pituitary apoplexy. The clinical picture included severe headache, visual disturbance, and hormonal deficit. Despite the absence of relevant clinical manifestations before the event, the diagnosis was confirmed by neuroimaging studies and hormonal evaluation. The therapeutic approach, which included surgical intervention, enabled partial recovery of visual and hormonal function. This case highlights the importance of surveillance of patients with pituitary macroadenomas, even when they are clinically silent, as they can present acute and severe complications such as pituitary apoplexy.

Palabras clave : pituitary apoplexy; pituitary neoplasms; headache; hypopituitarism.

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