Resumen

RUIZ CANO, Viviana Raquel et al. Primary adrenal insufficiency associated with systemic mycosis. Rev. virtual Soc. Parag. Med. Int. [online]. 2025, vol.12, n.1, e12142510.  Epub 27-Mayo-2025. ISSN 2312-3893.  https://doi.org/10.18004/rvspmi/2312-3893/2025.e12142510.

Primary adrenal insufficiency, or Addison's disease, is a rare and usually progressive disorder caused by hypoperfusion of the cortex. In the past, tuberculosis was considered the main infectious cause of this entity. However, at present, autoimmunity represents the main etiology.

We describe the case of a 50-year-old male patient with arterial hypertension and a history of pulmonary, lymph node, and meningeal tuberculosis, who completed his anti-bacillary treatment 7 years ago.

He presented with 2 months of vomiting with progression to oral intolerance, accompanied by weight loss and asthenia. Computed tomography showed irregular enlargement of both adrenals. A CT-guided biopsy was performed, and a histopathological study reported Histoplasma.

Palabras clave : adrenal insufficiency; extrapulmonary tuberculosis; histoplasmosis..

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