Resumen

HERNANDEZ NAVAS, Jorge Andrés et al. Advanced nasal neuroendocrine carcinoma: response to treatment and management of anemia in a palliative patient. Rev. virtual Soc. Parag. Med. Int. [online]. 2025, vol.12, n.1, e12142508.  Epub 27-Mar-2025. ISSN 2312-3893.  https://doi.org/10.18004/rvspmi/2312-3893/2025.e12142508.

Advanced nasal neuroendocrine carcinoma is a rare malignant tumor originating in the nasal cavity and paranasal sinuses. It is characterized by its high aggressiveness and tends to present in advanced stages, with infiltration of underlying bone structures. Diagnosis is confirmed by biopsy and histology, which usually shows poor neuroendocrine differentiation. Treatment is usually multimodal, including chemotherapy, radiotherapy, and in some cases, surgery. Neoadjuvant chemotherapy with cisplatin and etoposide improves survival in these patients.

We present the case of a 54-year-old female patient with stage IV A nasal neuroendocrine carcinoma, in palliative treatment with chemotherapy based on cisplatin and etoposide, and management of associated iron deficiency anemia. The patient showed a positive response to treatment, with scheduled follow-up to monitor her hematologic status and adjust supportive treatment.

Palabras clave : neuroendocrine carcinoma; iron deficiency anemia; chemotherapy..

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