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Revista Virtual de la Sociedad Paraguaya de Medicina Interna
versión On-line ISSN 2312-3893
Resumen
CARVAJAL OVIEDO, Cindy Julissa et al. Therapeutic inertia in the management of hypertension in older adults: clinical implications. Rev. virtual Soc. Parag. Med. Int. [online]. 2025, vol.12, n.1, e12132501. Epub 27-Mar-2025. ISSN 2312-3893. https://doi.org/10.18004/rvspmi/2312-3893/2025.e12132501.
Cardiovascular diseases continue to be the leading cause of morbidity and mortality in the world, generating a significant burden of disease in global health systems. Arterial hypertension (AHT) is one of the most prevalent cardiovascular disorders in the world, with more than 1 billion cases estimated globally. According to data from the World Health Organization, only 2 out of 10 people with HTN are under control, and one of the global health goals for 2030 is to reduce the prevalence of HTN by up to 33%. This may be caused by the omission to intensify drug therapy when necessary (therapeutic inertia). Therapeutic inertia is more frequent in patients at high risk of secondary or adverse events, such as older adults. It is believed that this could be a potential risk factor for cardiovascular outcomes, seeking a change in traditional algorithms and controversial paradigms. However, discrepancies persist in the literature regarding the approach to this topic. Considering its relevance and the need for evidence to meet global health goals, this review aimed to critically analyze the most recent evidence on therapeutic inertia in blood pressure control in older adults.
Palabras clave : blood pressure; hypertension; elderly; therapeutics; risk factors for heart disease; treatment compliance and adherence.












