Resumen

MONTIEL-ALFONSO, Miguel Angel; FERREIRA-ROMAN, Sandra; SANCHEZ, Ana Liz  y  MARECOS, Ricardo. Serological profile of transfusion-transmissible infections in blood donors at a referral hospital in Paraguay. Mem. Inst. Investig. Cienc. Salud [online]. 2026, vol.24, n.1, e24122602.  Epub 28-Mar-2026. ISSN 1812-9528.  https://doi.org/10.18004/mem.iics/1812-9528/2026.e24122602.

The identification of transfusion-transmissible infections is essential to ensure the safety of blood components administered to patients. This study aimed to determine the seropositivity rate of major infectious markers among donors at a referral hospital. A cross-sectional, observational, and descriptive study was conducted throughout 2024, analyzing the serological results of all donors who met the selection criteria established by the Pan American Health Organization. A total of 29,313 donations were recorded, of which 1,979 (6.75%) tested reactive for at least one marker. The average age was 38 years; most donors were male (77.78%) and replacement donors (90%). The most frequent markers were: syphilis (3.61%), total antibodies against hepatitis B core antigen (1.24%), Chagas disease (0.89%), hepatitis C (0.35%), and human T-lymphotropic viruses types 1 and 2 (0.28%). Systematic screening in blood banks is essential to ensure the quality and safety of transfusion practices.

Palabras clave : blood donors; transmissible diseases; transfusion; infectious diseases.

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