Introduction:

The incidence of invasive candidiasis varies from region to region, and its presence depends on many associated factors. It is a frequent cause of morbidity and mortality in premature newborns.

Objective:

To describe the clinical, epidemiological, and microbiological profile of invasive candidiasis in newborns at the Dr. Percy Boland Rodríguez Women's Hospital in Bolivia during 2023.

Materials and Methods:

This was an observational, descriptive and cross-sectional study based on a review of medical records and positive cultures for Candida spp. in blood, urine, cerebrospinal fluid, and other body fluids, corresponding to the year 2023.

Results:

The overall incidence of invasive candidiasis was 6.7 per 1000 live births, with a higher prevalence in males (73%). Candida albicans was the most frequently identified species. All cases received parenteral nutrition (median: 16 days), broad-spectrum antibiotics for more than 12 days, invasive mechanical ventilation (average: 12.6 days), and central catheterization (average of three catheters placed per patient). Abdominal involvement was present in 38% of cases.

Conclusions:

There is a considerable incidence of invasive candidiasis in a national referral hospital in Bolivia. Early recognition allows for the necessary therapeutic and/or prophylactic decisions to be made to avoid future complications.

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