<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2413-4341</journal-id>
<journal-title><![CDATA[Revista Paraguaya de Reumatología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. parag. reumatol.]]></abbrev-journal-title>
<issn>2413-4341</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Paraguaya de Reumatología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2413-43412023000100010</article-id>
<article-id pub-id-type="doi">10.18004/rpr/2023.09.01.10</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Lupus eritematoso sistémico masculino, reporte de características clínicas y serológicas en población pediátrica Mexicana]]></article-title>
<article-title xml:lang="en"><![CDATA[Male systemic lupus erythematosus, report of clinical and serological characteristics in Mexican pediatric population]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres]]></surname>
<given-names><![CDATA[Yessenia Hernández]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Herrera]]></surname>
<given-names><![CDATA[Iris Paola García]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vera]]></surname>
<given-names><![CDATA[Luis Alberto Aparicio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital para el Niño Poblano Departamento de Pediatría, ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital para el Niño Poblano Departamento de Reumatología Pediátrica ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>México</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<volume>9</volume>
<numero>1</numero>
<fpage>10</fpage>
<lpage>15</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S2413-43412023000100010&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S2413-43412023000100010&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S2413-43412023000100010&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: El lupus eritematoso sistémico es una enfermedad autoinmune compleja con numerosas manifestaciones clínicas y de laboratorio. La incidencia aumenta notablemente en la mujer. El motivo del predominio en el género femenino aún está en estudio. Se ha descrito en algunos estudios que el diagnóstico de lupus en población pediátrica masculina puede tener peor pronóstico con afectación más severa. Métodos: En este trabajo se describen las características clínicas y serológicas de una población pediátrica mexicana en un hospital mexicano de tercer nivel. Resultados: El trastorno renal fue más alto que otros informes, incluidos los informes de América Latina. Los síntomas constitucionales también fueron muy frecuentes. Y dentro del perfil inmunológico destacamos la positividad de anticuerpos anti-ADN, el consumo de complemento y el anticoagulante lúpico positivo. Conclusión: Creemos que el mejor conocimiento sobre poblaciones homogéneas podría mejorar las opciones de tratamiento. El lupus masculino en nuestro grupo pediátrico mexicano tuvo una mayor incidencia de afectación renal, en comparación con otros estudios reportados en población latinoamericana.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: Systemic lupus erythematosus is a complex autoimmune disease with nu- merous clinical and laboratory manifestations. The incidence increases markedly in woman. The reason for the predominance in the female gender is still under study. It has been des- cribed in some studies that the diagnosis of lupus in the male pediatric population may have a worse prognosis with more severe involvement. Methods: In this work we described the clinical and serological characteristics in a Mexican pediatric population in a tertiary Mexican hospital. Results: Kidney disorder was high than other reports, including the Latin American reports. Constitutional symptoms were very frequent as well. And within the immunological profile we highlight the positivity for anti-DNA antibodies, the consumption of complement and the positive lupus anticoagulant. Conclusion: We believed that the better knowledge about homogeneous populations could improve treatment options. Male lupus in our Mexican pediatric group has more renal disorder than other latin American groups.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Lupus]]></kwd>
<kwd lng="es"><![CDATA[sexo masculino]]></kwd>
<kwd lng="es"><![CDATA[características clínicas]]></kwd>
<kwd lng="es"><![CDATA[características serológicas]]></kwd>
<kwd lng="en"><![CDATA[Lupus]]></kwd>
<kwd lng="en"><![CDATA[male sex]]></kwd>
<kwd lng="en"><![CDATA[clinical features]]></kwd>
<kwd lng="en"><![CDATA[serologic features.]]></kwd>
</kwd-group>
</article-meta>
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