<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2312-3893</journal-id>
<journal-title><![CDATA[Revista Virtual de la Sociedad Paraguaya de Medicina Interna]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. virtual Soc. Parag. Med. Int.]]></abbrev-journal-title>
<issn>2312-3893</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Paraguaya de Medicina Interna]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2312-38932019000100134</article-id>
<article-id pub-id-type="doi">10.18004/rvspmi/2312-3893/2019.06(01)134-141</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Sarcoidosis atípica en un joven con úlceras cutáneas e hipercalcemia]]></article-title>
<article-title xml:lang="en"><![CDATA[Atypical sarcoidosis in a young man with skin ulcers and hipercalcemia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Dajaro Castro]]></surname>
<given-names><![CDATA[Leonel Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alvarado]]></surname>
<given-names><![CDATA[Daniel Andrés]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zuñiga Pineda]]></surname>
<given-names><![CDATA[Byron]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Calle Caamaño]]></surname>
<given-names><![CDATA[Carlos Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Montenegro Mayorga]]></surname>
<given-names><![CDATA[Silvia Elizabeth]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Especialidades Espíritu Santo Facultad de Medicina Hospital Luis Vernaza]]></institution>
<addr-line><![CDATA[Guayaquil ]]></addr-line>
<country>Ecuador</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Luis Vernaza Servicio de Nefrología ]]></institution>
<addr-line><![CDATA[Guayaquil ]]></addr-line>
<country>Ecuador</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Técnica Particular de Loja  ]]></institution>
<addr-line><![CDATA[Guayaquil ]]></addr-line>
<country>Ecuador</country>
</aff>
<pub-date pub-type="pub">
<day>01</day>
<month>03</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>01</day>
<month>03</month>
<year>2019</year>
</pub-date>
<volume>6</volume>
<numero>1</numero>
<fpage>134</fpage>
<lpage>141</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S2312-38932019000100134&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S2312-38932019000100134&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S2312-38932019000100134&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN La sarcoidosis es una enfermedad inflamatoria sistémica idiopática que afecta principalmente a los pulmones. Las manifestaciones extrapulmonares ocurren aproximadamente en 30% de los pacientes. Los sitios más comunes de enfermedad extrapulmonar incluyen la piel, los globos oculares, el sistema reticuloendotelial, el sistema musculoesquelético, las glándulas exócrinas, el corazón, los riñones y el sistema nervioso central. Presentamos un caso clínico de sarcoidosis con afectación de ganglios linfáticos periféricos, alteración renal y cutánea sin afectación pulmonar el cual representa un desafío diagnóstico por la ausencia de las características típicas de esta patología.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Sarcoidosis is an idiopathic systemic inflammatory disease that mainly affects the lungs. Extrapulmonary manifestations occur in approximately 30% of patients. The most common sites of extrapulmonary disease include the skin, eyeballs, reticuloendothelial system, musculoskeletal system, exocrine glands, heart, kidneys, and central nervous system. We present a clinical case of sarcoidosis with involvement of peripheral lymph nodes, renal and cutaneous alterations without pulmonary involvement, which represents a diagnostic challenge due to the absence of the typical characteristics of this pathology.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[sarcoidosis]]></kwd>
<kwd lng="es"><![CDATA[hipercalcemia]]></kwd>
<kwd lng="es"><![CDATA[úlcera cutánea]]></kwd>
<kwd lng="en"><![CDATA[sarcoidosis]]></kwd>
<kwd lng="en"><![CDATA[hipercalcemia]]></kwd>
<kwd lng="en"><![CDATA[skin ulcer]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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