<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2307-3349</journal-id>
<journal-title><![CDATA[Revista de salud publica del Paraguay]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. salud publica Parag.]]></abbrev-journal-title>
<issn>2307-3349</issn>
<publisher>
<publisher-name><![CDATA[INSTITUTO NACIONAL DE SALUD - MSP Y BS]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2307-33492018000100009</article-id>
<article-id pub-id-type="doi">10.18004/rspp.2018.junio.9-15</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Perfil de utilización de antibióticos en hospitales de tercer y cuarto nivel de atención de tres departamentos de Paraguay, 2017]]></article-title>
<article-title xml:lang="en"><![CDATA[Profile of antibiotic use in hospitals of third and fourth level of care of three departments of Paraguay, 2017]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Aguilar]]></surname>
<given-names><![CDATA[Gloria]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A3"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rios-González]]></surname>
<given-names><![CDATA[Carlos Miguel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
<xref ref-type="aff" rid="A a"/>
<xref ref-type="aff" rid="A3"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Estigarribia]]></surname>
<given-names><![CDATA[Gladys]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Kawabata]]></surname>
<given-names><![CDATA[Aníbal]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sanabria]]></surname>
<given-names><![CDATA[Gabriela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortiz]]></surname>
<given-names><![CDATA[Analía]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Royg]]></surname>
<given-names><![CDATA[María del Carmen]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cano]]></surname>
<given-names><![CDATA[Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Caaguazú Instituto de Investigación Regional en Salud ]]></institution>
<addr-line><![CDATA[Cnel. Oviedo ]]></addr-line>
<country>Paraguay</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Centro de Investigación y Recursos para el Desarrollo  ]]></institution>
<addr-line><![CDATA[Asunción ]]></addr-line>
<country>Paraguay</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Nacional de Caaguazú Facultad de Ciencias Médicas ]]></institution>
<addr-line><![CDATA[Cnel. Oviedo ]]></addr-line>
<country>Paraguay</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,Ministerio de Salud Pública y Bienestar Social Hospital de Trauma &#8220;Prof. Dr. Manuel Giani&#8221; ]]></institution>
<addr-line><![CDATA[Asunción ]]></addr-line>
<country>Paraguay</country>
</aff>
<aff id="Af5">
<institution><![CDATA[,Ministerio de Salud Pública y Bienestar Social Instituto de Medicina Tropical ]]></institution>
<addr-line><![CDATA[Asunción ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2018</year>
</pub-date>
<volume>8</volume>
<numero>1</numero>
<fpage>9</fpage>
<lpage>15</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S2307-33492018000100009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S2307-33492018000100009&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S2307-33492018000100009&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: Los antibióticos constituyen uno de los grupos farmacológicos de mayor prescripción y uso, ocupando el primer o segundo lugar en los gastos de farmacia de un hospital. Se estima que el 70% el uso de los antibióticos es inadecuado.  Objetivo:  Determinar el perfil de utilización de antibióticos en hospitales de tercer y cuarto nivel de atención de tres departamentos de Paraguay durante el 2017.  Material y métodos:  Estudio observacional, descriptivo de corte transversal con muestreo probabilístico. El diseño muestral considera como estratos los niveles de atención: cuarto y de tercer nivel de atención donde se seleccionaron hospitales en forma aleatoria en 3 departamentos. Se realizó un corte de prevalencia de una semana y se contabilizo la proporción bajo tratamiento con antibióticos y en caso de estar recibiendo ATB el motivo de indicación, tipo de antibiótico, vía de administración, dosis, intervalo, tiempo de antibioticoterapia.  Resultados:  Fueron incluidos en el estudio, 638 pacientes, el 63,67%(403) fueron mujeres, y el 26,09% (162) tenía una edad mayor a 50 años. El 70,69% (451) utilizo antibiótico, el 53,27% (236) de los casos se utilizó con fines profilácticos. El 34,60% (219) no uso de manera adecuada el antibiótico.  Conclusión: La proporción de uso de antibiótico y uso inadecuado fueron elevados. En su mayoría fueron con fines profilácticos Considerando la elevada utilización de antimicrobianos es imperativo desarrollar estrategias de control de prescripciones a través de comisiones de control de infección además de proporcionar una educación continua a los profesionales de salud a nivel hospitalario.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: Antibiotics are one of the pharmacological groups of greater prescription and use, occupying the first or second place in the pharmacy expenses of a hospital. It is estimated that 70% of the use of antibiotics is inadequate.  Objective: To determine the profile of antibiotic use in hospitals of third and fourth level of attention of three departments of Paraguay during 2017.  Material and methods:  Observational study, descriptive cross section with probabilistic sampling. The sample design considers levels of care as strata: fourth and third level of care where hospitals were randomly selected in 3 departments of Paraguay during 2017. A prevalence cut of one week was carried out and the proportion under treatment was counted with antibiotics and in case of receiving ATB the indication reason, type of antibiotic, route of administration, dose, interval, time of antibiotic therapy.  Results: Sixty-eight patients were included in the study, 63.67% (403) were female, and 26.09% (162) were older than 50 years. 70.69% (451) used antibiotics, 53.27% (236) of the cases were used for prophylactic purposes. 34.60% (219) did not use the antibiotic properly.  Conclusion: The proportion of antibiotic use was 70.69%, most were for prophylactic purposes and the highest proportion of the indications of antibiotics in hospitals is inadequate, in turn 34.60% of antibiotics are used improperly. For all the above, it is imperative to implement intervention strategies and control the use of antibiotics to reduce the use of antibiotics in hospitals.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Profilaxis Antibiótica]]></kwd>
<kwd lng="es"><![CDATA[Farmacorresistencia Microbiana]]></kwd>
<kwd lng="es"><![CDATA[Uso Racional de los Medicamentos]]></kwd>
<kwd lng="en"><![CDATA[Antibiotic Prophylaxis]]></kwd>
<kwd lng="en"><![CDATA[Microbial drug resistanc]]></kwd>
<kwd lng="en"><![CDATA[Rational use of medicines]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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