<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2072-8174</journal-id>
<journal-title><![CDATA[Revista del Nacional (Itauguá)]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Nac. (Itauguá)]]></abbrev-journal-title>
<issn>2072-8174</issn>
<publisher>
<publisher-name><![CDATA[Hospital Nacional (Itauguá)]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2072-81742020000100055</article-id>
<article-id pub-id-type="doi">10.18004/rdn2020.0012.01.055-070</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Morbimortalidad en pacientes con neutropenia febril del Hospital Nacional, 2017-2019]]></article-title>
<article-title xml:lang="en"><![CDATA[Morbidity and mortality in patients with febrile neutropenia from the Hospital Nacional, 2017-2019]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Real Delor]]></surname>
<given-names><![CDATA[Raúl Emilio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Dávalos Ortiz]]></surname>
<given-names><![CDATA[José Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Itapúa Facultad de Medicina Postgrado en Medicina Interna]]></institution>
<addr-line><![CDATA[Encarnación ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2020</year>
</pub-date>
<volume>12</volume>
<numero>1</numero>
<fpage>55</fpage>
<lpage>70</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S2072-81742020000100055&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S2072-81742020000100055&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S2072-81742020000100055&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  la neutropenia es una situación de riesgo de infecciones que puede generar elevada morbimortalidad. La fiebre es un marcador de riesgo de complicaciones.  Objetivo:  determinar la relación de la fiebre con la morbimortalidad y la duración de la internación en pacientes con neutropenia.  Metodología:  diseño observacional, retrospectivo, realizado en pacientes adultos con neutropenia internados en el Hospital Nacional (Itauguá, Paraguay) entre 2017 y 2019. Se conformaron dos cohortes: una con neutropénicos con fiebre y otra sin fiebre. La variable independiente fue la fiebre y las dependientes fueron la morbimortalidad, los días de internación y las complicaciones nosocomiales. Todos los pacientes fueron tratados con los protocolos vigentes. El estudio contó con la aprobación del Comité de Ética de la Universidad Nacional de Itapúa.  Resultados: ingresaron al estudio 169 sujetos con neutropenia, con edad media 44 ± 20 años, siendo 51,4 % del sexo femenino. La cohorte con fiebre se constituyó con 76 sujetos, tuvo una media de internación de 20 ± 10 días y mortalidad 30,9 %. La cohorte sin fiebre se conformó con 96 sujetos, tuvo una media de internación de 15 ± 10 días y mortalidad 10,7 %.  Conclusiones:  la fiebre en los pacientes con neutropenia se asocia a mayor mortalidad, complicaciones nosocomiales y estancia hospitalaria.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  neutropenia is a situation with risk of infections that can generate high morbidity and mortality. Fever is a risk factor for complications.  Objective:  to determine the relation of fever with morbidity and mortality, and length of hospitalization in patients with neutropenia.  Methodology:  observational, retrospective design, carried out on adult patients with neutropenia hospitalized at the National Hospital (Itauguá, Paraguay) between 2017 and 2019. Two cohorts were formed: one with neutropenic patients with fever and the other without fever. The independent variable was fever and the dependent variables were morbidity and mortality, hospitalization days, and nosocomial complications. All patients were treated with current protocols. The study had the approval of the Comité de Ética of the Universidad Nacional de Itapúa.  Results:  169 subjects with neutropenia entered the study, with a mean age of 44 ± 20 years, being 51,4 % female. The fever cohort was made up of 76 subjects, with a mean hospitalization of 20 ± 10 days and mortality of 30,9 %. The fever-free cohort was made up of 96 subjects, had a mean hospitalization of 15 ± 10 days and mortality of 10,7 %.  Conclusions:  fever in patients with neutropenia is associated with higher mortality, nosocomial complications and hospital stay.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[neutropenia]]></kwd>
<kwd lng="es"><![CDATA[neutropenia febril]]></kwd>
<kwd lng="es"><![CDATA[mortalidad]]></kwd>
<kwd lng="es"><![CDATA[hospitalización]]></kwd>
<kwd lng="en"><![CDATA[neutropenia]]></kwd>
<kwd lng="en"><![CDATA[febrile neutropenia]]></kwd>
<kwd lng="en"><![CDATA[mortality]]></kwd>
<kwd lng="en"><![CDATA[hospitalization]]></kwd>
</kwd-group>
</article-meta>
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