<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2312-3893</journal-id>
<journal-title><![CDATA[Revista Virtual de la Sociedad Paraguaya de Medicina Interna]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. virtual Soc. Parag. Med. Int.]]></abbrev-journal-title>
<issn>2312-3893</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Paraguaya de Medicina Interna]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2312-38932026000100318</article-id>
<article-id pub-id-type="doi">10.18004/rvspmi/2312-3893/2026.e13142618</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Abordaje del penfigoide ampolloso en paciente de edad avanzada]]></article-title>
<article-title xml:lang="en"><![CDATA[Management of bullous pemphigoid in elderly patients]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Centurión Villalba]]></surname>
<given-names><![CDATA[Aramí María]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Fleitas Goiriz]]></surname>
<given-names><![CDATA[Braulio Mauricio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Aldama Caballero]]></surname>
<given-names><![CDATA[Arnaldo Benjamín]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Asunción Facultad de Ciencias Médicas Hospital de Clínicas]]></institution>
<addr-line><![CDATA[San Lorenzo ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2026</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2026</year>
</pub-date>
<volume>13</volume>
<numero>1</numero>
<fpage>318</fpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S2312-38932026000100318&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S2312-38932026000100318&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S2312-38932026000100318&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Las enfermedades ampollosas en un paciente de edad avanzada representan un reto diagnóstico y terapéutico, entre las cuales se debe considerar al penfigoide ampolloso como una de las más prevalentes. Suele ser más frecuentemente idiopático, aunque hay algunos casos que se asocian a la utilización de ciertos fármacos empleados de forma rutinaria en patologías comunes como diabetes mellitus y enfermedad de Parkinson, además con una relación histórica con ciertas neoplasias. Presentamos el caso de un paciente de la tercera edad con diagnóstico de penfigoide ampolloso por los hallazgos clínicos confirmados en la anatomía patológica, donde se consideró la etiología farmacológica y neoplásica.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Bullous diseases in elderly patients represent a diagnostic and therapeutic challenge, among which bullous pemphigoid should be considered one of the most prevalent. It is usually idiopathic, although there are some cases associated with the use of certain drugs routinely used in common pathologies such as diabetes mellitus and Parkinson's disease, as well as a historical relationship with certain neoplasms. We present the case of an elderly patient diagnosed with bullous pemphigoid based on clinical findings confirmed by pathological anatomy, where pharmacological and neoplastic etiology was considered.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[penfigoide ampolloso]]></kwd>
<kwd lng="es"><![CDATA[enfermedades cutáneas vesiculoampollosas]]></kwd>
<kwd lng="es"><![CDATA[erupciones por medicamentos]]></kwd>
<kwd lng="en"><![CDATA[bullous pemphigoid]]></kwd>
<kwd lng="en"><![CDATA[vesicular-bullous skin diseases]]></kwd>
<kwd lng="en"><![CDATA[drug eruptions]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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