<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2072-8174</journal-id>
<journal-title><![CDATA[Revista del Nacional (Itauguá)]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Nac. (Itauguá)]]></abbrev-journal-title>
<issn>2072-8174</issn>
<publisher>
<publisher-name><![CDATA[Hospital Nacional (Itauguá)]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2072-81742023000200051</article-id>
<article-id pub-id-type="doi">10.18004/rdn2023.dic.02.051.063</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Características clínicas y tiempo de inicio de tratamiento trombolítico en pacientes con Accidente Cerebrovascular Isquémico en la Unidad de ICTUS del Servicio de Urgencias del Hospital de Clínicas]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical characteristics and time of initiation of thrombolytic treatment in patients with Ischemic Cerebrovascular Accident in the Stroke Unit of the Emergency Service of the Hospital de Clínicas]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Báez Melgarejo]]></surname>
<given-names><![CDATA[Luis Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ortiz Galeano]]></surname>
<given-names><![CDATA[Ignacio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Nacional de Asunción Facultad de Ciencias Médicas Hospital de Clínicas]]></institution>
<addr-line><![CDATA[San Lorenzo ]]></addr-line>
<country>Paraguay</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Nacional de Asunción Facultad de Ciencias Médicas Hospital de Clínicas, Docente-Investigador, Especialista en Medicina Interna]]></institution>
<addr-line><![CDATA[San Lorenzo ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2023</year>
</pub-date>
<volume>15</volume>
<numero>2</numero>
<fpage>51</fpage>
<lpage>63</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S2072-81742023000200051&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S2072-81742023000200051&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S2072-81742023000200051&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: la trombólisis intravenosa revolucionó la terapéutica de los pacientes con accidentes cerebrovasculares isquémicos.  Objetivo:  determinar las características clínicas y tiempo de inicio de tratamiento trombolítico en pacientes con accidente cerebrovascular isquémico en la Unidad de ICTUS del Hospital de Clínicas.  Metodología:  estudio retrospectivo, observacional, descriptivo, transversal, muestreo no probabilístico, de pacientes con diagnóstico de accidente cerebrovascular isquémico ingresados en la Unidad de ICTUS del Hospital de Clínicas, desde enero del 2015 hasta junio del 2022. Se midieron variables sociodemográficas, tiempo de inicio de tratamiento trombolítico, NIHSS al ingreso, 24 horas y 5 días, escala ASPCT, glicemia, presión arterial sistólica y diastólica, factores de riesgo de enfermedad cardiaca, transformación hemorrágica.  Resultados:  10 % de los pacientes cumplieron criterios de trombólisis, edad media 62 ± 1, masculino 59 %. Promedio desde el ingreso hospitalario hasta el goteo del trombolítico fue 44±2 minutos y desde el inicio del cuadro hasta el goteo del trombolítico 195 ± 5 minutos. Los factores de riesgo cardiovascular más frecuentes fueron Hipertensión Arterial y Diabetes Mellitus, en 5 % de los trombolizados ocurrieron transformaciones hemorrágicas sintomáticas.  Conclusión: 10 % de los pacientes cumplieron criterios para trombólisis. La media desde el ingreso al hospital hasta el goteo del fibrinolítico fue de 44 minutos y desde el inicio del cuadro hasta el goteo del trombolítico 195 ± 5 minutos. Los factores de riesgo de enfermedad cardiaca más frecuentes fueron la Hipertensión Arterial y Diabetes Mellitus, ocurrió 5% de transformación hemorrágica sintomática.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  intravenous thrombolysis revolutionized the therapy of patients with ischemic strokes.  Objective:  to determine the clinical characteristics and time of initiation of thrombolytic treatment in patients with ischemic stroke in the Stroke Unit of the Hospital de Clínicas.  Methodology:  this was a retrospective, observational, descriptive, cross-sectional study, we used non-probabilistic sampling, of patients with a diagnosis of ischemic stroke admitted to the Stroke Unit of the Hospital de Clínicas, from January 2015 to June 2022. Sociodemographic variables, start time of thrombolytic treatment, NIHSS at admission, 24 hours and 5 days, ASPCT scale, glycemia, systolic and diastolic blood pressure, risk factors for heart disease, hemorrhagic transformation.  Results:  10 % of patients met thrombolysis criteria, with a mean age of 62 ± 1,59 % were male. The average time from hospital admission to the thrombolytic drip was 44 ± 2 minutes and from the onset of symptoms to the thrombolytic drip was 195 ± 5 minutes. The most frequent cardiovascular risk factors were High Blood Pressure and Diabetes Mellitus; symptomatic hemorrhagic transformations occurred in 5 % of the thrombolyzed patients.  Conclusion:  10 % of patients met criteria for thrombolysis. The mean time from hospital admission to the fibrinolytic drip was 44 minutes and from the onset of symptoms to the thrombolytic drip was 195 ± 5 minutes. The most frequent risk factors for heart disease were High Blood Pressure and Diabetes Mellitus, 5 % of symptomatic hemorrhagic transformation occurred.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[accidente cerebrovascular]]></kwd>
<kwd lng="es"><![CDATA[terapia trombolítica]]></kwd>
<kwd lng="es"><![CDATA[factores de riesgo de enfermedad cardiaca]]></kwd>
<kwd lng="en"><![CDATA[stroke]]></kwd>
<kwd lng="en"><![CDATA[thrombolytic therapy]]></kwd>
<kwd lng="en"><![CDATA[heart disease risk factors]]></kwd>
</kwd-group>
</article-meta>
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