<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2072-8174</journal-id>
<journal-title><![CDATA[Revista del Nacional (Itauguá)]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Nac. (Itauguá)]]></abbrev-journal-title>
<issn>2072-8174</issn>
<publisher>
<publisher-name><![CDATA[Hospital Nacional (Itauguá)]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2072-81742023000100068</article-id>
<article-id pub-id-type="doi">10.18004/rdn2023.jun.01.068.081</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Manifestaciones atípicas en pacientes con Chikungunya]]></article-title>
<article-title xml:lang="en"><![CDATA[Atypical manifestations in patients with Chikungunya]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jarolín]]></surname>
<given-names><![CDATA[Dora Montiel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Torres de Taboada]]></surname>
<given-names><![CDATA[Estela]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arce Kita]]></surname>
<given-names><![CDATA[Juan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Jarolín Montiel]]></surname>
<given-names><![CDATA[Magali]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Taboada Torres]]></surname>
<given-names><![CDATA[Verónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez]]></surname>
<given-names><![CDATA[Luis Fernando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Ministerio de Salud Pública y Bienestar Social Centro Médico Nacional-Hospital Nacional Departamento de Medicina Interna]]></institution>
<addr-line><![CDATA[Itauguá ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<volume>15</volume>
<numero>1</numero>
<fpage>68</fpage>
<lpage>81</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S2072-81742023000100068&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S2072-81742023000100068&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S2072-81742023000100068&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  las manifestaciones atípicas por el virus Chikungunya son poco frecuentes, presentándose sobre todo en adultos mayores y en lactantes, se presenta en los extremos de la vida, la frecuencia va del 9 % - 33 %. La mortalidad es elevada.  Objetivo:  presentar 4 pacientes con manifestaciones atípicas atribuida a la infección por el virus Chikungunya, internados en el Departamento de Medicina Interna y el Departamento de Urgencias Adulto del Hospital Nacional en febrero-marzo 2023 describir las manifestaciones atípicas de 4 pacientes posteriores a la infección por CHIKV reportadas en la literatura. Algunas manifestaciones fueron neurológicas, cardiovasculares, cutáneas, oculares, renales y otras.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: atypical manifestations due to the Chikungunya virus are rare, appearing mainly in older adults and infants, it occurs at the extremes of life, the frequency ranges from 9 % - 33 %. Mortality is high.  Objective: to present 4 patients with atypical manifestations attributed to Chikungunya virus infection, admitted to the Department of Internal Medicine and the Adult Emergency Department of the National Hospital in February-March 2023. describe the atypical manifestations of 4 patients after CHIKV infection reported in the literature. Some manifestations were neurological, cardiovascular, cutaneous, ocular, renal, and others.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[manifestaciones atípicas]]></kwd>
<kwd lng="es"><![CDATA[Chikungunya]]></kwd>
<kwd lng="es"><![CDATA[miocarditis]]></kwd>
<kwd lng="es"><![CDATA[encefalitis]]></kwd>
<kwd lng="es"><![CDATA[sangrado SNC]]></kwd>
<kwd lng="en"><![CDATA[atypical manifestations]]></kwd>
<kwd lng="en"><![CDATA[chikungunya]]></kwd>
<kwd lng="en"><![CDATA[myocarditis]]></kwd>
<kwd lng="en"><![CDATA[encephalitis]]></kwd>
<kwd lng="en"><![CDATA[CNS bleeding]]></kwd>
</kwd-group>
</article-meta>
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