<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1683-9803</journal-id>
<journal-title><![CDATA[Pediatría (Asunción)]]></journal-title>
<abbrev-journal-title><![CDATA[Pediatr. (Asunción)]]></abbrev-journal-title>
<issn>1683-9803</issn>
<publisher>
<publisher-name><![CDATA[Sociedad Paraguaya de Pediatría]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1683-98032018000200115</article-id>
<article-id pub-id-type="doi">10.31698/ped.45022018002</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Dengue y Bradicardia: caracterización clínica y evolución]]></article-title>
<article-title xml:lang="en"><![CDATA[Dengue and Bradycardia: clinical characterization and course]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Godoy]]></surname>
<given-names><![CDATA[Laura]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arce]]></surname>
<given-names><![CDATA[Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pavlicich]]></surname>
<given-names><![CDATA[Viviana]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mesquita]]></surname>
<given-names><![CDATA[Mirta]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital General Pediátrico &#8220;Niños de Acota Ñu&#8221;  ]]></institution>
<addr-line><![CDATA[San Lorenzo ]]></addr-line>
<country>Paraguay</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2018</year>
</pub-date>
<volume>45</volume>
<numero>2</numero>
<fpage>115</fpage>
<lpage>118</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_arttext&amp;pid=S1683-98032018000200115&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_abstract&amp;pid=S1683-98032018000200115&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.iics.una.py/scielo.php?script=sci_pdf&amp;pid=S1683-98032018000200115&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  Las alteraciones de la conducción cardiaca y bradicardia, están descriptos en el Dengue, aunque su fisiopatología no es del todo clara.  Objetivo:  Describir las características clínicas y evolución de los pacientes con dengue y bradicardia.  Metodología:  estudio observacional, descriptivo, longitudinalde seguimiento de una cohorte. Fueron incluidos pacientes de 1 mes a 18 años ingresados en el Servicio de Urgencias del Hospital General Pediátrico Niños de Acosta Ñu, con diagnóstico de dengue, que presentaron bradicardia y que hayan tenido seguimiento hasta la desaparición del síntoma. Variables edad, sexo, clasificación del dengue, resultado del electrocardiograma (ECG), radiografía de tórax, inicio de bradicardia, frecuencia cardiaca al egreso, duración de la bradicardia en el seguimiento y días de hospitalización. Los datos fueron analizados en SPSSv 21, utilizando la estadística descriptiva. El protocolo fue aprobado por el Comité de ética.  Resultados:  En el periodo de estudio se hospitalizaron 310 pacientes con Dengue. El 6,4% (20/310) presentó bradicardia. La edad media fue de 12,7±2,8 años, con predominio del sexo masculino. Algunos pacientes ya tenían bradicardia en el momento del ingreso (9/20), mientras que otros lo presentaron en el curso de la hospitalización (11/20). Hubo un caso de bloqueo AV y los demás presentaron bradicardia sinusal (19/29). La bradicardia persistió al alta en la mayoría de los pacientes (18/20) y se resolvió durante la primera semana de seguimiento. El promedio de días de hospitalización fue 7,1±1,9.  Conclusión:  La frecuencia de bradicardia fue del 6,4%. La mayoría de los pacientes tenía el diagnóstico de Dengue Grave. Un alto porcentaje continuaba con bradicardia al momento del alta sin manifestaciones clínicas de dengue. En la mayoría de los pacientes se presentó durante la hospitalización y se normalizó durante el seguimiento al alta.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: Alterations in cardiac conduction and bradycardia are described in Dengue, although its pathophysiology is not entirely clear.  Objective:  To describe the clinical characteristics and course of patients with dengue and bradycardia.  Methodology:  This was an observational, descriptive and longitudinal cohort study. We enrolled patients from 1 month to 18 years of age who were admitted to the Emergency Department of the Acosta Ñu Children's General Hospital with a diagnosis of dengue, who presented bradycardia and who had follow-up until the disappearance of the symptom. The variables were age, sex, dengue classification, electrocardiogram (ECG) results, chest x-ray, onset of bradycardia, heart rate at discharge, duration of bradycardia during follow-up and days of hospitalization. Data were analyzed in SPSSv 21, using descriptive statistics. The protocol was approved by the Hospital Ethics Committee.  Results:  During the study period, 310 patients with Dengue were hospitalized. 6.4% (20/310) had bradycardia. The average age was 12.7 ± 2.8 years, with a predominance of males. Some patients already had bradycardia at the time of admission (9/20), while others developed it during hospitalization (11/20). There was one case of AV block and the others presented sinus bradycardia (19/29). Bradycardia persisted at discharge in most patients (18/20) and resolved during the first week of follow-up. The average number of hospitalization days was 7.1 ± 1.9.  Conclusions:  The frequency of bradycardia was 6.4%. The majority of patients had a diagnosis of severe dengue. A high percentage of patients continued to have bradycardia at discharge with no other clinical manifestations of dengue. In the majority of patients, bradycardia presented during hospitalization and normalized at their discharge follow-up.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Fiebre Dengue]]></kwd>
<kwd lng="es"><![CDATA[bradicardia]]></kwd>
<kwd lng="es"><![CDATA[pacientes pediátricos.]]></kwd>
<kwd lng="en"><![CDATA[Dengue fever]]></kwd>
<kwd lng="en"><![CDATA[bradycardia]]></kwd>
<kwd lng="en"><![CDATA[pediatric patients.]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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