Abstract

TORRES-BOGGINO, Estela; TABOADA, Verónica; MONTIEL, Dora  and  VELAZQUEZ, Graciela. Hospitalization and mortality risk factors of patients with systemic lupus erythematoso in Paraguay. Rev. cient. cienc. salud [online]. 2023, vol.5, e5118.  Epub Aug 30, 2023. ISSN 2664-2891.  https://doi.org/10.53732/rccsalud/2023.e5118.

Introduction. Hospitalization in patients with systemic lupus erythematosus (SLE) is frequent. Objective. To determine hospitalization and mortality risk factors in patients with SLE admitted to the National Hospital from January 2016 to December 2019. Material and methods. observational descriptive with an analytical component and cross-sectional study. Patients over 15 years of age with a diagnosis of SLE were included. The variables were age, sex, comorbidities, abandonment of treatment, education, SLEDAI score, clinical characteristics and death. Results were expressed as frequency for qualitative variables, and mean and standard deviation for continuous variables. To establish associations between the qualitative variables, the chi-square test was used; and the strength of the association were measured by the Odds Ratio (OR) with its 95% confidence interval (CI). Results. 130 patients (mean age 31 ± 12.1) corresponding to 170 hospitalizations were studied, 92% were women and arterial hypertension presented 51.4% of the patients. The frequent cause of hospitalization was disease activity (75.8%). A 21.5% were admitted to the ICU (intensive care unit). Education level, treatment abandonment and disease activity were associated to mortality (p<000001). Conclusions. Disease activity was a frequent cause of hospitalization and associated to patient death. Treatment abandonment was also found to be a risk factor for death.

Keywords : hospitalization; systemic lupus erythematosus; risk factors..

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )