Abstract

DELGADILLO, Lorena et al. Risk factors associated with mortality in pediatric oncology patients admitted to intensive care at a University Hospital in Paraguay: a 3-year experience. Rev. cient. cienc. salud [online]. 2022, vol.4, n.1, pp.63-74. ISSN 2664-2891.  https://doi.org/10.53732/rccsalud/04.01.2022.63.

Introduction. The survival of patients with childhood neoplasia has improved considerably thanks to the progress in diagnosis and multidisciplinary treatment. Objective. to determine the mortality risk factors in patients admitted to intensive care (PICU) at a teaching hospital in Asunción, Paraguay. Methodology. A retrospective review of the medical charts of cancer patients admitted to the PICU of the Hospital de Clínicas from January 2014 to December 2016 was carried out. Results. 874 patients admitted to the PICU, 150 (17.2%) patients had cancer. Mean age was 9.8 ± 5.2 years; 51% female. They had readmission (12%), other comorbidity (48%), emergency admission (67.3%). Previous days of hospitalization in the ward was an average 6.5 ± 10.9 and in the intensive care unit 6.9 ± 13.7 days. The type of cancer was 52% hematological. 82% of patients presented failure of one or more organs and mortality was 19.3%. Several risk factors for mortality were identified by bivariate analysis, but by multivariate analysis only five variables were associated with death: age ≥10 years (p=0.047), PIM2 ≥10 (p=0.001), mucositis (p= 0.004), neurological failure (p= 0.001) and renal failure (p= 0.001). Conclusion. Overall mortality was lower than that reported in other series, which was higher in those older than 10 years, with mucositis, neurological and renal organ failure.

Keywords : mortality; risk factors; pediatrics; intensive care unit; neoplasia.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )