Abstract

MANAVELLA, Gustavo D.; MANAVELLA, Diego D.  and  RUIZ V, Oscar. Pregnancy and live birth rates in young women with diminished ovarian reserve. Rev. cient. cienc. salud [online]. 2021, vol.3, n.1, pp.6-13. ISSN 2664-2891.  https://doi.org/10.53732/rccsalud/03.01.2021.06.

Introduction: Results of assisted reproductive techniques are unfavorable in infertile patients under 40 years of age with decreased ovarian reserve, as compared to those of the same age with normal ovarian reserve. Aim. To investigate the pregnancy and live birth rates in infertile young patients with diminished ovarian reserve. Materials & methods. Retrospective and descriptive study of women less than 40 years old, undergoing in vitro fertilization, with embryos transferred on days 3 and 5, with anti-mullerian hormone (AMH) values of less than 1,1 ng/ml) and antral follicle count (AFC) of 7 or less. Results. A total of 45 patients were included, 51% between 35 to 39 years old. The mean AMH value was 0.59 ng/dL, the mean AFC was 4.73 follicles and oocyte retrieval, a mean of 4.4. The clinical pregnancy rate and live birth rates did not yield statistically significant results when compared to each clinical outcome, except when compared embryos transferred on day 3 with day 5 (p<0.0001). A significant correlation was found between levels of AMH and number of follicles (p=0.0034) as well as number of retrieved oocytes (p=0.0159). Conclusions. In young patients with diminished ovarian reserve undergoing in vitro fertilization cycles, clinical pregnancy rates significantly increase when embryos are transferred on day 5.

Keywords : live birth; pregnancy rate; ovarian reserve; anti-Müllerian hormone; in vitro fertilization; embryo transfer.

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