Introduction:

Antibiotics have been the most effective tool for the fight against infectious and communicable diseases. However, in recent times its effectiveness has been affected by antimicrobial resistance, which in turn is largely determined by the appropriate or inappropriate use of antibiotics.

Objective:

To determine the specific frequency of antibiotic use in the General Hospital of the Department of San Pedro Paraguay - Korea in 2019. Methodology: An observational, descriptive study on the use of antibiotics was done. Patients hospitalized from August 26 to 29, 2019 were included. The reason for indication, class of antibiotic and compliance with therapeutic guidelines were evaluated. The data was uploaded and analyzed on the RedCap platform.

Results:

A total of 62 patients were included. Of this patients 53.23% were female, aged 21 to 27 years (19.35%). The specific frequency of antibiotic use was 91.94%, of which 38.60% was for prophylaxis and 61.40% for therapeutic use. The most frequent diagnosis was pneumonia (31.43%) and the most frequent prescriber was the responsible physician (85.48%). Among the therapeutic cases, it was observed that 94.29% were for empirical use. The most frequently used antibiotic families were: first and third generation cephalosporin 25.64%. A 52.63% of inappropriate use of antibiotics was observed.

Conclusion:

The high frequency of antimicrobial use and a significant proportion of inappropriate use in the Paraguay-Korea General Hospital have been highlighted. It is important to establish antimicrobial use optimization programs and strengthen health care-associated infection committees.