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Revista Paraguaya de Reumatología
On-line version ISSN 2413-4341
Abstract
OCAMPOS, Erika Belén Castillo et al. Treatment of joint manifestations in the chronic phase of chikungunya fever. Rev. parag. reumatol. [online]. 2023, vol.9, n.2, pp.64-70. Epub Dec 30, 2023. ISSN 2413-4341. https://doi.org/10.18004/rpr/2023.09.02.64.
Chikungunya fever is caused by an RNA arbovirus belonging to the Togaviridae family of the alphavirus genus, called "chikungunya virus", this virus is vectored by Aedes aegypti and Aedes albopictus. In its acute phase, the disease is manifested by fever, arthritis or severe arthralgia, myalgia, headache, photophobia, lymphadenopathy and skin rashes. The symptoms can progress to a subacute to chronic phase, where joint manifestations and fatigue persist. A bibliographic search was carried out in the PubMed, Cochrane, Dovepress and SciELO databases, using the keywords: chikungunya and chikunguña, crossed with the words: chronic arthritis and treatment. A total of 16 articles were included: 6 review articles, 1 systematic review, 4 original articles, 2 clinical trials, 1 letter to Editor letter and 2 case reports. Among the pharmacological options, methotrexate is the most studied drug and competes with the effects of NSAIDs. Non-pharmacological therapies are physiotherapy and physical therapy, used as complements to pharmacological therapy. The use of home therapies, including homeopathy, could also be added, mainly addressing the psychological and cultural factors of the patients.
Keywords : chikungunya; arthritis; treatment.