Abstract

JAROLIN, Dora Montiel  and  SAMUDIO, Margarita. Clinical characteristics of patients with Systemic Lupus Erythematosus, at debut and relapse. Rev. parag. reumatol. [online]. 2023, vol.9, n.2, pp.48-52.  Epub Dec 30, 2023. ISSN 2413-4341.  https://doi.org/10.18004/rpr/2023.09.02.48.

Introduction: The clinical forms of presentation of systemic lupus erythematosus (SLE) are varied, as well are the relapses that occur in the course of the disease. Objective: To describe the onset and relapses in a cohort of patients with SLE. Methodology. Observational, descriptive, cross-sectional study of patients with SLE who attended the National Hospital, during the period 2022 to 2023. The variables analyzed were sociodemographic, forms of onset and relapses. Results: 47 patients between 14 and 68 years of age (mean: 29.6 ±12 years) were included in the study, 91.5% female, 59.5% from the interior of the country, with secondary education (68.1%) and housewife occupation (55.3%). The duration of illness was on average 48.7 ±37.1 months. The most common form of onset was polyarthralgia (55.3%), followed by nephritis (27.7%). In relapse, nephritis was more frequent (44.7%), followed by polyarticular pain (40.4%). The most frequent cause of relapse was treatment abandonment (34.0%). Conclusion: The majority of patients were young women who presented the disease with arthralgia, followed by kidney involvement. Relapses presented with nephritis. The main cause of relapses were treatment abandonment.

Keywords : Systemic Lupus Erythematosus; onset; relapses.

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