Abstract

VAZQUEZ, Marcos et al. Epidemiological and clinical profile of patients with Sjögren‘s Syndrome of the Rheumatology Department of the Hospital de Clínicas. Psecopy Project. Preliminary data. Rev. parag. reumatol. [online]. 2021, vol.7, n.1, pp.2-6. ISSN 2413-4341.  https://doi.org/10.18004/rpr/2021.07.01.2.

Sjögren‘s syndrome is a systemic autoimmune disease characterized by dry mucous membranes and systemic involvement. The aim of the present study was to describe the clinical epidemiological characteristics of patients with primary Sjögren‘s Syndrome included in the Psecopy cohort who meet the ACR/EULAR 2016 criteria and evaluated at the Rheumatology Department of the Hospital de Clínicas of San Lorenzo. Results: 33 patients with primary Sjögren‘s syndrome were included, of which 31 (93.93%) were females and 2 (6.01%) were males. The average age at the time of diagnosis of primary Sjögren‘s syndrome was 46.12 years. The average duration of the disease was 2.10 years. The most frequently associated comorbidities were arterial hypertension (21.21%) followed by hypothyroidism (18.18%). Salivary biopsy was performed on 12.12% of patients that did not meet Chisholm and Mason criteria, and a predominant focus score of 3 was found. In relation to ESSDAI, articular involvement was found in 51.51%, glandular in 54.54%, articular in 51.51%, pulmonary, lymphadenopathy and biological domain in 12.12%, hematological and constitutional domain in 9.09%, cutaneous and renal in 6.06%, central and peripheral nervous system in 3.03% of patients. Low disease activity was found in 63.63% of patients, while moderate and high activity was found in 21.21% and 15.15% of patients respectively, according to the ESSDAI scale. No neoplasms were found.

Keywords : Sjogren‘s syndrome; Clinical features..

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