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Revista Paraguaya de Reumatología

On-line version ISSN 2413-4341


MENDIETA-ZERON, Samara; RUIZ-GONZALEZ, Mateo Sebastian  and  MARTIN-DE SARO, Mónica Denisse. Vitamin D levels and its association with disease activity and quality of life in patients with juvenile idiopathic arthritis from ISSEMYM Toluca Maternal Children‘s Hospital. Rev. parag. reumatol. [online]. 2019, vol.5, n.2, pp.43-50. ISSN 2413-4341.


Juvenile Idiopathic Arthritis (JIA) is one of the most common chronic inflammatory diseases in pediatrics, it is known that vitamin D has a direct effect on bone and muscle health, in the last decade functions have been found on the immune response and inflammation. Studies on chronic inflammatory diseases in pediatric age including JIA. The objective of this work is to determine if there is an association between vitamin D levels and disease activity and quality of life of patients with JIA.


Cohort, observational and analytical study where, prior approval by the Research Ethics Committee of the Hospital, Vit D levels were determined and with the result CHAQ and JADAS71 tests were applied, in patients with JIA diagnosis, in the Pediatric Rheumatology consultation, information was collected from 28 patients diagnosed with JIA.


An average of Vitamin D levels of 21.53 ng / mL (+/- 7.04 ng / mL) was found with a minimum of 6.9 ng / mL and a maximum of 38.9 ng / mL. The results obtained for the quality of life evaluated through the CHAQ Questionnaire reported that 30.8% were with zero limitation, 30.8% mild limitation, 26.9% moderate limitation and 11.5% severe limitation. When using the JADAS test to assess disease activity, 42.3% of patients have inactive disease; 7.7% with low activity, 26.9% with moderate activity and 23.1% with high activity.


Although if it is found with an average in the population studied of vitamin D, in ranges of insufficiency, no relationship was found between these levels with the disease activity and quality of life of those of patients with JIA.

Keywords : Juvenile Idiopathic Arthritis; Vitamin D; Disease Activity; Quality of Life.

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