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Revista Paraguaya de Reumatología

versão On-line ISSN 2413-4341


ALBRECHT, María Teresa Romero de. Antiphospholipid syndrome: clinical and immunological spectrum and treatment. Rev. parag. reumatol. [online]. 2018, vol.4, n.2, pp.39-42. ISSN 2413-4341.

Antiphospholipid syndrome (APS) is characterized by hypercoagulability, manifested by venous and /or arterial thrombosis, increased maternal and fetal mortality and morbidity, and serological abnormalities mediated by antiphospholipid antibodies. Of these, the best known are lupus anticoagulant (AL), anticardiolipin (aCL) and antiB2 glycoprotein I. This is an observational, descriptive study of a case series of patients with APS from a part of the Paraguayan population. In our population (n=25) we have 92% females and average age was 37,8 years. Deep venous thrombosis (DVT) and ischemic cerebrovascular accidents (CVA) were the predominant clinical manifestations. Secondary APS was present in 84% (21/25) of patients, most of them (70%) corresponding to SLE. Mortality was 8%.

Palavras-chave : Antiphospholipid syndrome,clinic; treatment.

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