Introduction:

The appearance of a new variant of coronavirus has unleashed a pandemic related to a severe respiratory distress syndrome due to SARS-CoV-2. The first manifestations associated with this new syndrome were purely respiratory. However, with the different studies it was evidenced not only pulmonary involvement, but also systemic especially at the neurological level where patients present central and peripheral symptoms of coronavirus involvement.

Materials and Methods:

A review was conducted using databases such as: PubMed, Scopus, Embase, Cochrane Library, SciELO, including observational studies, review articles, clinical guidelines, which evaluated the presence of neurological manifestations in patients diagnosed from 2019 to 2021.

Results:

Twenty-six articles were included in which it was observed that nonspecific neurological manifestations such as headache was the most common with a presentation of 30%. Specific neurological manifestations occur with a frequency of about 3% but with greater severity, including seizures and stroke.

Conclusions:

It is a pathology where its main characteristic is pulmonary symptomatology. However, some patients have specific neurological manifestations which are less frequent but have a more severe character and in contrast the nonspecific neurological manifestations are more frequent but do not endanger the patient's life. Such symptomatology is crucial when approaching a patient with COVID-19 and should be kept in mind in timely medical care.

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