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Revista Virtual de la Sociedad Paraguaya de Medicina Interna

On-line version ISSN 2312-3893


IBANEZ FRANCO, Elvis Javier et al. Characterization of sepsis in adult patients of the Hospital Nacional. Rev. virtual Soc. Parag. Med. Int. [online]. 2022, vol.9, n.1, pp.62-70. ISSN 2312-3893.


Sepsis is a pathology that affects a large number of people around the world, and it continues to be a major health problem due to its high mortality.


To describe the characteristics of sepsis in adult patients of the Hospital Nacional Hospital, Itauguá, Paraguay.


Observational, retrospective, descriptive, cross-sectional study in which all adult men and women from the 2020-2021 period were included. The research was approved by the Ethics Committee of the National University of Itapúa.


The sample consisted of 92 patients, the mean age was 59±18 years, 56.5% were male, 52.2% came from urban areas, primary schooling prevailed (46.8%). Comorbidities were present in 84.8%: arterial hypertension and diabetes mellitus were the most frequent. The most frequent focus of sepsis was pulmonary (35.9%), followed by skin and soft tissues (26.1%). The most used antibiotics were cephalosporins (22.8%), penicillin derivatives (17.4%) and a combination of quinolone and lincosamide (17.4%). In 38%, antibiotic therapy was started after 4 hours, in 31.5% between 3 and 4 hours and in 30.4% before 2 hours. Germs were isolated in 53.2% of the cases, 65.2% required hospitalization in intensive care, of which 70% died.


The mean age was 59 years and male sex predominated. The most frequent comorbidity was arterial hypertension. The main source of origin was the lung. The most frequently used antibiotics were cephalosporins. Only in 30.4% of cases, antibiotics started within 2 hours of diagnosis. Overall mortality was 45.65%.

Keywords : sepsis; mortality; comorbidity; antibacterials.

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