SciELO - Scientific Electronic Library Online

vol.8 issue2Frequency of burnout syndrome in Internal Medicine residents of the Hospital de ClínicasGuide for the protection and circulation of health personnel and patients in hospitalized patients rooms of the Medical Clinic Service, National author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista Virtual de la Sociedad Paraguaya de Medicina Interna

On-line version ISSN 2312-3893


PEDREANEZ SANTANA, Adriana Beatriz; MUNOZ CASTELO, Nelson Enrique; TENE SALCAN, Diego Mauricio  and  ROBALINO CONGACHA, Jorge Guillermo. Analysis of the role of vitamin D in the immune defense against COVID-19 in older adults. Rev. virtual Soc. Parag. Med. Int. [online]. 2021, vol.8, n.2, pp.76-88. ISSN 2312-3893.

Coronavirus disease 2019 (COVID-19) was announced as a global pandemic by the World Health Organization on February 11, 2020. From that moment, challenges have arisen regarding how to optimally support the immune system in the general population, and especially in older adults. There is much evidence that the severity of SARS-CoV-2 infections varies widely with age, being generally more severe in the elderly. An optimal immune response depends on proper diet and nutrition to adequately counter the infection. Several studies have shown the importance of vitamin D as a key factor in regulating immune responses. In this review, we analyze the role of vitamin D in the immune response during SARS-CoV-2 infection with special emphasis on older adults.

Keywords : aging; COVID-19; inflammation; vitamin D; coronavirus infections; immune system.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )