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Revista Virtual de la Sociedad Paraguaya de Medicina Interna

On-line version ISSN 2312-3893


CORREA, Carlos et al. Euglycemic diabetic ketoacidosis associated with sodium-glucose cotransporter-2 inhibitors use. Rev. virtual Soc. Parag. Med. Int. [online]. 2020, vol.7, n.2, pp.124-130. ISSN 2312-3893.

A 48-year-old woman with a history of type 2 diabetes mellitus treated with empaglifozine came to consultation after 8 hours of abdominal pain, nausea, vomiting, and shortness of breath. After the physical examination, the patient was alert, allergic, pale, with dry mucosa, tachypnea, tachycardia, and with diffuse abdominal pain without signs of peritoneal irritation. The results of his laboratory showed a serum glucose of 115 mg/dL (70-100 mg/dL), arterial blood gasometry with metabolic acidosis with an elevated gap anion of 20 mmol/L. Urine analysis reported ketonuria (150 ketone bodies) and HbA1C was 12.4% (4.8% -6%). A surgical cause of abdominal pain was ruled out and she was finally diagnosed with euglycemic diabetic ketoacidosis secondary to the use of sodium-glucose cotransporter inhibitors 2.

Keywords : diabetes mellitus; euglycemic diabetic ketoacidosis; sodium-glucose cotransporter 2 inhibitors.

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