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Revista Virtual de la Sociedad Paraguaya de Medicina Interna
On-line version ISSN 2312-3893
Abstract
ORTIZ GALEANO, Ignacio; BRUNSTEIN PEDROZO, Hadhara and LOPEZ OVELAR, Helen María Rocío. Hypothyroidism as a risk factor for dyslipidemia and obesity. Rev. virtual Soc. Parag. Med. Int. [online]. 2020, vol.7, n.2, pp.55-61. ISSN 2312-3893. https://doi.org/10.18004/rvspmi/2312-3893/2020.07.02.55.
Introduction:
Hypothyroidism is associated with increased cardiovascular risk, dyslipidemia, overweight and obesity.
Objective:
To determine the relationship between hypothyroidism and the risk of developing obesity and/or dyslipidemia in patients of the outpatient clinic of the First Chair of Medical Clinic of Hospital de Clínicas between 2015 and 2017.
Material and method:
Design of retrospective cohorts. The inclusion criteria were patients with a probable diagnosis in the first consultation of hypothyroidism and who had data on TSH, FT4, body mass index and lipid profile. Demographic variables, TSH, FT4, lipid profile, and body mass index were measured.
Results:
Files of two hundred and forty-six patients that met the inclusion criteria were included in the study, 80.1% was women, the mean age was 47±3.6 years, and 19% had hypothyroidism. The most frequent dyslipidemia was hypercholesterolemia and obesity occurred mainly in women. Hypothyroidism was significantly associated with the development of dyslipidemia (RR 1.7; p 0.009) compared to the euthyroid population, and no association was found with the presence of obesity (RR 1; p 0.960).
Conclusion:
Patients with hypothyroidism are at higher risk of having dyslipidemia. Hypothyroidism was not associated with the presence of obesity.
Keywords : hypothyroidism; dyslipidemia; overweight; obesity.
