Abstract

MALVETTI MAFFEI, María Victoria; BAEZ CABRAL, Santiago Adelio  and  SANTA CRUZ, Francisco Vicente. Thyroid dysfunction in Type 2 diabetes mellitus patients.: A frequent association?. Rev. virtual Soc. Parag. Med. Int. [online]. 2016, vol.3, n.1, pp.33-41. ISSN 2312-3893.  https://doi.org/10.18004/rvspmi/2312-3893/2016.03(01)33-041.

Introduction: Thyroid dysfunction (TD) is frequently observed in Type 2 diabetes mellitus (DM2) patients being the hypothyroidism the most common. Objectives: To determine the frequency of TD in DM2 patients consulting at the Fist Chair of Medical Clinic of the Hospital de Clínicas (San Lorenzo, Paraguay) from January to December, 2013. Material and Methods: Analytical retrospective observational design that included men and women older than 18 years old. We excluded patients receiving drugs that affect thyroid function, those that were thyroidectomized and chronic renal patients. Results: We included 254 patients and found DT in 9.45% (n=24), previous diagnosis 8.26% (n=21) and new cases 1.18 % (n=3). We found hypothyroidism in 66.7 % (n=16), being clinical hypothyroidism 41.6% (n=10) of them and sub-clinical hypothyroidism 25% (n=6). Also, we determined hyperthyroidism in 33.3 (n=8), being clinical hyperthyroidism 20.8% (n=5) of them and sub-clinical hyperthyroidism 12.5% (n=3). Out of the 254 patients, 179 were women (22 with TD) and 97 men (2 with TD), (OR 6.6 (1.5-28.9) p = 0.003); 126 were older than 50 years old (17 with TD) and 128 were < 50 years old (7 with TD): (OR 2.6 (1.1-6.7) p= 0.03). Conclusions: The frequency of TD in DM2 patients was 9.45%, with predominance in women and in those older than 50 years being the most frequent dysfunction, clinical hypothyroidism.

Keywords : thyroid dysfunction; diabetes mellitus; hyperthyroidism; hypothyroidism.

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