Abstract

GONZALEZ CASCAN, Yngrid Margarita  and  TORRES DE TABOADA, Estela. Correlation between the random urine protein-creatinine ratio and 24-hour proteinuria. Rev. virtual Soc. Parag. Med. Int. [online]. 2015, vol.2, n.1, pp.74-92. ISSN 2312-3893.  https://doi.org/10.18004/rvspmi/2312-3893/2015.02(01)74-092.

Introduction: The quantification of proteins in urine is a study that evaluates kidney involvement in some diseases. The measurement can be made through the urine protein-creatinine ratio. Objective: To determine the correlation between the urine protein-creatinine ratio and 24-hour urine protein. Methodology: A cross-sectional prospective observational descriptive study with analytical component and non-probabilistic sampling was performed. Sixty patients who had risk factors of chronic renal disease and attended the National Hospital (Itauguá) in 2014 were included. Twenty four-hour urine and a random urine sample were analyzed to estimate the protein-creatinine ratio. Results: A very significant correlation (r= 0.9 p < 0.001) was observed between the values of the protein-creatinine ratio in a random urine and 24-hour urine protein with a sensitivity of 94.1% (IC95% 79-100), specificity of 100% (IC95% 98-100%), positive predictive value of 100% (IC95% 96-100) and negative predictive value of 97.7% (IC95% 92-100). Conclusion: The protein-creatinine ratio is useful to detect proteinuria in a non-nephrotic range.

Keywords : proteinuria; 24-hour proteinuria; urine protein-creatinine ratio; arterial hypertension; systemic lupus erythematosus.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )