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Revista Virtual de la Sociedad Paraguaya de Medicina Interna

On-line version ISSN 2312-3893

Abstract

ZACARIAS LEGUIZAMON, José. Most frequentadverse reactions to antiretroviral drugs. Rev. virtual Soc. Parag. Med. Int. [online]. 2014, vol.1, n.2, pp.13-27. ISSN 2312-3893.  https://doi.org/10.18004/rvspmi/2312-3893/2014.01(02)13-027.

Introduction: Adverse reactions to antiretroviral drugs are obstacles for the compliance and good adherence because of their severity, the treatment dropouts and/or the replacement of the drug. Objective: To describe the most frequently observed adverse reactions to antiretroviral drugs. Patients and methods: Retrospective observational design carried out in adult men and women, HIV carriers, who attended the Comprehensive Care Service between November, 2007 and December, 2012. Results: One hundred ninety patients were included and 59 cases (31%) presented side-effects to HAART. Mean age was 35 years (range: 19-63 years) and 62.2% of the subjects were men. Neuropsychological (28%), dermatologic (22%) and hematologic (21%) manifestations predominated.

Keywords : HIV; antiretroviral drugs; adverse reactions to drugs.

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