SciELO - Scientific Electronic Library Online

vol.14 número1Análisis Situacional de Muertes Maternas en Paraguay: alcances del 2008-2018Componentes biosociales y enfermedades prevalentes de la infancia en menores de 5 años del Bañado Sur de Asunción índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO


Revista de salud publica del Paraguay

versión impresa ISSN 2224-6193versión On-line ISSN 2307-3349


VIVEROS, Guiomar; GONZALEZ VAZQUEZ, Gloria; MENDEZ, Julieta  y  GALEANO, Deisy. Persistence of signs and symptoms 6 months after chikungunya infection in patients from a Public Hospital in Paraguay. Rev. salud publica Parag. [online]. 2024, vol.14, n.1, pp.15-22. ISSN 2307-3349.


Chikungunya virus (CHIKV) causes a disease with well-documented acute manifestations, but there is limited data on the persistence of symptoms and long-term sequelae.


To evaluate the persistence of signs, symptoms, and associated factors in patients with CHIKV infection during a 6-month post-infection follow-up.

Material and Methods:

An ambispective cohort study that included confirmed cases of CHIKV reported in April 2023 in Coronel Oviedo, Paraguay. Interviews were conducted at 1, 3 and 6 months post-infection. Demographic characteristics, comorbidities, rheumatic, and symptomatic manifestations were analyzed.


333 participants were enrolled, with 170 patients completing the 6-month follow-up. At 6 months, the following symptoms persisted: back pain (61.2%), arthritis (57.1%), headache (54.1%), fatigue (51.2%), myalgia (49.4%), weakness (47.6%), depression (45.9%), and arthralgia (45.9%). The persistence of arthritis (OR 7.54, p=0.008) and myalgia (OR 3.24, p=0.031) at 6 months was higher in the 36-45 age group.


High persistence of musculoskeletal symptoms and fatigue up to 6 months post-infection, with a decreasing trend but exacerbation of depression. Age between 36-45 years was associated with greater persistence. Comprehensive follow-up protocols, investigation of pathophysiological mechanisms, and strengthening prevention are required, given the individual and socioeconomic impact of the disease.

Palabras clave : chikungunya virus; musculoskeletal pain; follow-up studies.

        · resumen en Español     · texto en Español     · Español ( pdf )