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Revista de salud publica del Paraguay

versión impresa ISSN 2224-6193versión On-line ISSN 2307-3349


ESTIGARRIBIA-SANABRIA, Gladys et al. Characteristics of acute chikungunya virus infection in children: an epidemiological study in the Department of Caaguazú, Paraguay. Rev. salud publica Parag. [online]. 2024, vol.14, n.1, pp.10-14. ISSN 2307-3349.


The rapid transmission and severe symptoms associated with acute chikungunya virus (CHIKV) infection in children make it a highly concerning health issue.


This study aimed to describe the characteristics of acute chikungunya virus infection in children from the Department of Caaguazú, Paraguay.

Material and Methods:

A retrospective observational study was conducted in the Department of Caaguazú, Paraguay, in 2023, with all patients who came to the Regional Hospital within 5 days of developing characteristic symptoms of acute CHIKV infection and tested positive for the virus by RT-PCR. Patients with Dengue or Zika infections were excluded. We collected data on clinical characteristics using a standardized case record form and created an electronic dataset for analysis.


A total of 461 children were included in the study. 51.6% were women. Cases were divided into groups based on pediatric age: infants (0-23 months, n=88, 19.1%), preschoolers (2-5 years, n=115, 24.9%), schoolchildren (6-11 years, n=163, 35.4%), and adolescents (12-17 years and 11 months, n=95, 20.6%). Schoolchildren and adolescents experienced a higher prevalence of myalgia (64.6%) and arthralgia (63.7%). Vomiting (89%), headache (89.4%), and retro-orbital pain (95%) were more common in preschoolers, schoolchildren, and adolescents, while rash (39.5%) and petechiae (18.5%) were more prevalent in infants. Four children died during the study period.


The 2023 CHIKV virus epidemic in Paraguay had different clinical presentations depending on the age of the affected children, with fatal outcomes occurring in a small percentage of cases.

Palabras clave : chikungunya; epidemic; childhood.

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