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Revista de salud publica del Paraguay

Print version ISSN 2224-6193On-line version ISSN 2307-3349


RIOS-GONZALEZ, Carlos Miguel et al. Side effects of COVID-19 vaccines in paraguayan health personnel: exploratory study. Rev. salud publica Parag. [online]. 2021, vol.11, n.2, pp.24-29. ISSN 2307-3349.


Paraguay began on monday, february 22, 2021, the vaccination campaign against covid-19. All vaccines, including those for COVID-19, carry the potential for side effects such as fatigue, fever, headaches, myalgia, chills, nausea, diarrhea, and injection site pain.


Identify the proportion of side effects of vaccines against COVID-19 in health personnel in Paraguay.


Cross-sectional study. The population was made up of health personnel vaccinated by COVID-19 in the first quarter of 2021. The variables were sex, age, history of COVID-19, underlying diseases, the name of the vaccine received, symptoms, time of appearance of symptoms and their duration, use of paracetamol and whether or not medical attention was required.


146 participated, of which 68.5% were female and 38.4% were less than 30 years old. 72.6% of the participants received the Oxford-AstraZeneca vaccine and 76.1% had no history of Covid-19. 60.4% of the study population had symptoms after COVID-19 vaccination. The most common symptoms were arm pain (84.1%) weakness / fatigue (75.9%), headache (65.5%), joint pain (48.8%), chills (41.4%), fever (39.1%), and nausea (33.3). The time to onset of symptoms was immediate (up to 1 hour after vaccination), mostly 43.3% in the Oxford-AstraZeneca vaccine compared to the other vaccines (11.8%). Symptoms lasted 1 day in 42.9% of cases.


The frequency of side effects was 60.4% of the population, however, the symptoms were mild and mostly lasted one day after the application. Surveillance in the general population is necessary at this stage during the launch of vaccination

Keywords : COVID-19; vaccine; AstraZeneca; symptoms; side effects.

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