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Revista de salud publica del Paraguay

Print version ISSN 2224-6193On-line version ISSN 2307-3349


BALMELLI, B; MUSSI, D; CANESE, J  and  SANDOVAL, J. Treatment of late sequels of scars in burns using the Fraction of the Vascular Stroma (SVF) derived from the adipose tissue from human lipoaspirates. Rev. salud publica Parag. [online]. 2018, vol.8, n.1, pp.27-34. ISSN 2307-3349.


The adipose tissue obtained by liposuction is an ideal source to isolate cells with therapeutic potential, cells of the vascular stromal fraction (FEV), which include mesenchymal stem cells. These cells have become one of the main tools of autologous cell therapy for varius medical applications, and in recent years various technologies have been developed for their isolation and clinical use. For its part the scars resulting from burns have functional and aesthetic sequelae for patients who suffer from it, what therapeutic challenges in relation to its improvement.


To demonstrate the functional and aesthetic effects of the application of the derived stromal vascular fraction of autologous adipose tissue for the treatment of late sequelae of burns.

Material and Methods:

Analytical, experimental, non-controlled trial with patients who had scars from burns in the Centro Nacional de Quemaduras y Cirugía Reconstructiva (CENQUER) in may 2017. Measurements were made with scales and optical microscopy for the evaluation of the characteristics of the scar before and after 6 months of the procedure.


There were no local or systemic complications related to the procedure and improvement was found with respect to the evaluation scales and optical microscopy. There was a noticeable benefit in the evolution of lesions, both aesthetic and clinical, in functional capacity as well as in angiogenesis. The remodeling of scars using fraction derived from adipose tissue of the vascular stroma can be considered as an alternative in the joint or isolated management of scars from burns with no morbidity for the patient.

Keywords : liposuction; scars; burns; derived stromal vascular fraction.

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