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Cirugía paraguaya

versión On-line ISSN 2307-0420


GONZALEZ, Lourdes et al. Effect of perioperative protocols of improved and conventional recovery on glycemia and the percentage of lymphocytes in patients with colorectal cancer at the National Institute of Cancer "Prof. Dr. Manuel Riveros". Cir. parag. [online]. 2019, vol.43, n.2, pp.19-23. ISSN 2307-0420.


This study was conducted based on the scientific evidence of the implementation of the ERAS and ACERTO protocols, of which the protocol called Enhanced Recovery was put together. It was adapted to the socioeconomic reality of the National Cancer Institute and seeks to reduce metabolic stress, the immune response and promote the patient's postoperative recovery.


To compare the effect of the perioperative protocols of improved and conventional recovery on glycaemia and the percentage of lymphocytes in patients with colorectal cancer.

Materials and Methods:

A quasi-experimental, nonrandomized, non-masked clinical trial of 34 patients with colorectal cancer undergoing open surgery was performed. A control group with conventional management (n = 18) and the intervention group (n = 16) in whom the improved recovery protocol was applied; the outcome variable was glycemia and lymphocyte count; Likewise, other clinical variables such as complications and demographics were measured.


The perioperative glycemic response in patients in the study group was 42±32.09 mg/dL and 5.25±52.81mg/dL in the intervention group with p=0.009; the percentage of lymphocytes in the control group was 13.77±10.95% and 7.18±5.21% in the intervention group, with p=0.015; statistically significant.


Applying the Improved Recovery Protocol is feasible and decreases the glycemic impact and the percentage of lymphocytes in relation to conventional management.

Palabras clave : multimodal approach, colorectalcancer, ERAS; ACERTO, hyperglycemia.

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