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Cirugía paraguaya

On-line version ISSN 2307-0420


AGUERO, Angel et al. Surgical Management of Myasthenia Gravis. Cir. parag. [online]. 2019, vol.43, n.2, pp.15-18. ISSN 2307-0420.


The disorders of neuromuscular transmission, are a rare but important cause of weakness in children and adults, manifested by a weakness that predominates in certain muscle groups and characteristically fluctuates in response to effort and rest. Within this group of disorders the most important is Myasthenia Gravis.


To know the surgical management of Myasthenia Gravis in the surgical services of the Hospital de Clínicas during the period from January 2008 to November 2018.

Material and Methodology:

Observational, descriptive, retrospective, cross-sectional study, from 2008 to 2018.


13 patients with the diagnosis of Myasthenia Gravis, predominance of the female sex, with an observed relation between both sexes of 2.25 / 1. The average age was 29.5 years. The most frequent clinical manifestations were palpebral ptosis, diplopia and generalized muscular weakness. Subtype IIB is the most frequent (Osserman). All were operated on, transsternal thymectomy in 84.6% and in 15.4% thymectomy by VATS. Thymic hyperplasia was found in 69.2%. Evolution; 23.1% are without medication, 46.1% medication in lower doses.


Remission of the disease was observed and an obvious postoperative clinical improvement in the vast majority of patients.

Keywords : Myasthenia Gravis; timectomy; thymoma.

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