Abstract

ALARCON, Leticia et al. Recurrent laryngeal papillomatosis with transformation lung carcinoma. Rev. Cir. Parag. [online]. 2013, vol.37, n.1, pp.27-30. ISSN 2307-0420.

ABSTRACT Introduction: Recurrent laryngeal papillomatosis (RLP) is caused by human papilloma virus (HPV) 6 and 11 subgroups. A small percentage (2%) can become malignant, transforming into squamous cell carcinoma, especially in cases with bronchopulmonary dissemination and frequent relapses. Objective: Report a case of aggressive evolution of juvenile laryngeal papilomatosis with malignant manifestation of it. Case Report: Female patient, 16 years old, born by vaginal delivery, with multiple recurrent laryngeal papillomatosis, even microsurgery and emergency tracheotomy. Consulted for progressive respiratory distress, feeling feverish, coughing and stitch type pain in left lung base. Entry with febrile, polipneica, inspiratory stridor, tracheacutaneou fistula and multiple papillary lesions. Chest CT revealed tumor mass in the left lower lobe, with teh other side injuries associated. she underwent a left lower lobectomy by thoracotomy. Pathology confirmed the presence of lung squamous cell carcinoma nodal metastases. The patient received adjuvant treatment, with stabilization the lesions on the other side at 2 years. Conclusion: Juvenile laryngeal papillomatosis is a generally benign entity that should be considered, not only for its eventual malignant transformation but also for its unpredictable local developments and septic respiratory compromise that can lead to death.

Keywords : Recurrent laryngeal papillomatosis; Human papillomavirus; Carcinoma of the lung.

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