Abstract

GONZALEZ BARRIOS, Laura Alicia. LEISHMANIOSIS CANINE: MOLECULAR TOOLS USED FOR DIAGNOSIS AND RESEARCH FROM BIOLOGICAL SAMPLES. Compend. cienc. vet [online]. 2018, vol.8, n.2, pp.36-43. ISSN 2226-1761.  https://doi.org/10.18004/compend.cienc.vet.2018.08.02.36-43.

Leishmaniasis, a nosological entity of parasitic origin and worldwide distribution, is considered zoonotic, as it affects humans, domestic and wild animals from around the world. The most important characteristic of canine Leishmaniasis is its extraordinary clinical polymorphism, which makes it difficult to choose a good laboratory method. Diagnostic methods available in the country for confirmation of clinical diagnosis are serological, cytological and molecular. Molecular methods have great advantages, however due to their lack of use in veterinary diagnostic centers and the lack of knowledge of most veterinarians, they are not implemented as routine diagnostic techniques. In neighboring countries and elsewhere in the world it is widely disseminated and in many cases is used as a basic test for the diagnosis of the disease, through the detection of parasitic DNA, from bone marrow biopsies, lymph nodes and other Tissues. Therefore, in the following article, the objective is to make known the molecular methods used in the world and in our country, with the objective of providing useful tools to the Veterinarian to arrive at the accurate diagnosis and to the researcher interested in knowing even more about the biology of the parasite.

Keywords : Leishmaniasis; diagnosis; DNA; molecular methods.

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