Abstract

PEDROZO PRIETO, R  and  DOMEL, B. VARIATIONS IN CALCIUM, PHOSPHORUS AND POTASSIUM SERUM CONCENTRATIONS IN DOGS WITH CHRONIC KIDNEY DISEASE AT DIFFERENT STAGES: A PRELIMINARY STUDY IN PARAGUAY. Compend. cienc. vet [online]. 2015, vol.5, n.1, pp.20-25. ISSN 2226-1761.  https://doi.org/10.18004/compend.cienc.vet.2015.05.01.20-25.

ABSTRACT. In order to evaluate changes in serum calcium (Ca), phosphorus (P) and potassium (K) in dogs with chronic kidney disease (CKD), 61 dogs with clinical diagnosis of CKD were classified into 5 stages according to the system of the International Renal Interest Society (IRIS). The values of urea, creatinine, calcium, phosphorus and potassium were determined by spectrophotometry and the results analyzed with statistical Kruskal Wallis and Spearman correlation. As a result, there were no differences when comparing the values of calcium in the 5 stages of CKD (p=0.19), but the frequency of hyperphosphatemia increased with the severity of CKD. Differences were observed when comparing the serum concentrations of phosphorus (p< 0.0001) having a significant increase only in stages 3 and 4. On the other hand, there was significant difference between the mean values of potassium in the stage 4 relative to the other phases (p< 0.0001). Serum concentrations of phosphorus and potassium were significantly and positively correlated with serum urea and creatinine (p < 0.0001 and 0.003). However calcium had a weak association with urea and weaker with creatinine, with positive correlations and not significant (p=0.87 and 0.09).

Keywords : calcium; phosphorus; potassium; dogs; chronic renal disease.

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