Resumo

BENITEZ-VILLALBA, Julio César; DORIVAL-GARCIA, Noemí; VILLALBA-VILLALBA, Nadia Mabel  e  VILCHEZ, José Luis. Validation of an analysis method for benzophenones in a soil sample through pressurized liquid extraction and liquid chromatograph coupled to tandem mass spectrometry. Rep. cient. FACEN [online]. 2018, vol.9, n.1, pp.51-63. ISSN 2222-145X.  https://doi.org/10.18004/rcfacen.2018.9.1.51.

In this research work an analytical methodology has been developed and validated for the determination and quantification of a family of benzophenones in soil samples, these compounds come from industrial processes, organic synthesis, cosmetics and sunscreens, which are not eliminated during the Treatment of waste water; The extraction variables have been optimized using the Pressurized Liquid Extraction (PLE) technique, the compounds were detected and quantified by a liquid chromatograph coupled to tandem mass spectrometry (MS / MS, QqQ), operating in positive ESI mode and negative, in SRM mode (monitoring of the selected reaction) with analyte separation in less than 6 minutes, using deuterated Benzophenone (BP-d-10) as internal standard; obtaining recoveries of analytes between 97.0% and 101.0% with the method. The detection limits were 0.05 to 0.90 ng g-1 and the quantification limit between 0.16 to 2.70 ng g-1. The analytical method has been detected is precise, sensitive, selective and accurate, with detection and quantification limits sufficiently low to detect this analytical method in the detection and quantification of these compounds in this environmental sample. This method offers a scientific innovation, since there are few published methods on the study of these microcontaminants in agricultural soils as a matrix studied.

Palavras-chave : Benzophenones; mass spectrometry; emerging contaminants; endocrine disruptor.

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