Abstract

ALUAN, Adid et al. Pulmonary alveolar proteinosis and lung injury induced by the use of electronic cigarettes or vapers (EVALI). Rev. Nac. (Itauguá) [online]. 2023, vol.15, n.1, pp.59-67. ISSN 2072-8174.  https://doi.org/10.18004/rdn2023.jun.01.059.067.

Pulmonary alveolar proteinosis is a diffuse disease due to the accumulation of surfactant in the alveoli that can cause dyspnea and progressively lead to respiratory failure. Although it is usually of immune etiology, there are secondary and congenital cases. E-cigarette induced lung injury (EVALI) is a recently described entity and has multiple clinical and histopathological expressions, among which only a couple of reports present pulmonary alveolar proteinosis as part of the spectrum. We describe the clinical case and management of one young man and analyze the possible cellular mechanisms that could generate this association.

Keywords : Pulmonary alveolar proteinosis; electronic cigarettes; vaping; EVALI; lung lavage; bronchoalveolar lavage; acute lung injury.

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