Introduction:

systemic lupus erythematosus (SLE) can affect the three celular series of the blood.

Objective:

to describe hematological alterations and activity markers in adult patients with SLE.

Methodology:

descriptive observational study performed in patients with SLE of the National Hospital in 2017-2018. Were excluded patients with immunosuppressants (cyclophosphamide, rituzimab), patients with drugs induled SLE, patients with overlap syndrome, patients with other autoimmune diseases.

Results:

88 patients were included, with an average age of 27 ± 15 years. There was a predominance of women (89%). Anemia was detected in 55%, leukopenia in 13%, lymphopenia in 32%, thrombocytopenia in 11%. ANA values ​​were high in 92% and anti DNA in 22%.

Conclusion:

the most frequent haematological compromise in adult patients with SLE was anemia, followed by leukopenia and thrombocytopenia.

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