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Revista del Nacional (Itauguá)
Print version ISSN 2072-8174
Abstract
GARCIA BELLO, Enrique and TORRES DE TABOADA, Estela. Hematological manifestations in adult patients with systemic lupus erythematosus. Rev. Nac. (Itauguá) [online]. 2019, vol.11, n.1, pp.5-16. ISSN 2072-8174. https://doi.org/10.18004/rdn2019.0011.01.005-016.
Introduction:
systemic lupus erythematosus (SLE) can affect the three celular series of the blood.
Objective:
to describe hematological alterations and activity markers in adult patients with SLE.
Methodology:
descriptive observational study performed in patients with SLE of the National Hospital in 2017-2018. Were excluded patients with immunosuppressants (cyclophosphamide, rituzimab), patients with drugs induled SLE, patients with overlap syndrome, patients with other autoimmune diseases.
Results:
88 patients were included, with an average age of 27 ± 15 years. There was a predominance of women (89%). Anemia was detected in 55%, leukopenia in 13%, lymphopenia in 32%, thrombocytopenia in 11%. ANA values were high in 92% and anti DNA in 22%.
Conclusion:
the most frequent haematological compromise in adult patients with SLE was anemia, followed by leukopenia and thrombocytopenia.
Keywords : systemic lupus erythematosus; anemia; leukopenia; plaquetopenia.