Abstract

MELGAREJO PANIAGUA, Patricia Alexandra; DENIS DOLDAN, Amado Emilio; FERREIRA GAONA, Marta Inés  and  DIAZ REISSNER, Clarisse Virginia. Complications in patients with systemic lupus erythematosus. Rev. Nac. (Itauguá) [online]. 2015, vol.7, n.1, pp.28-31. ISSN 2072-8174.  https://doi.org/10.18004/rdn2015.0007.01.028-031.

Introduction: Systemic Lupus Erythematosus (SLE) is an autoimmune disease of unknown origin that causes outbreaks episodes alternating with periods of remission. During outbreaks motivating hospitalization complications can occur. Objective: To identify complications in SLE patients admitted to the Internal Medicine Service of Central Hospital “Dr. Emilio Cubas” Institute for Social Welfare in 2013. Methods: Descriptive observational, retrospective, cross-sectional research. Patients not known carriers of SLE and who developed complications at the onset of the disease were excluded, as well as those with SLE who were admitted to the Internal Medicine Service from the Intensive Care Unit (ICU). Results: 40 patients affected were hospitalized during the study period, predominantly female (92.5%), with an average age of 38.8 years. Main symptoms in order of frequency were: respiratory (35.0%), neurological (25.0%) and febrile sensation (20.0%). The most common comorbidities present were hypertension (40.0%), another autoimmune disease (18.0%) and chronic kidney disease (15.0%). The most common complications were infection (67.5%), renal (22.5%), hematologic (20.0%) and neurological (20.0%). About the evolution of patients, 87.5% were discharged, 7.5% died and 5.0% were transferred to the ICU. The 3 deaths corresponded to infectious causes (septic shock). Conclusion: Infectious complications are a frequent reason for hospitalization in patients with SLE, because of the disease and the immunosuppressive therapy they are more likely to develop this complication.

Keywords : Autoimmunity, Lupus Erythematosus, Systemic, Hospitalization, Paraguay..

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