Abstract

CORREA RECALDE, Daiana María  and  REAL, Raúl. Manifestations of dengue in the kidney. Rev. Nac. (Itauguá) [online]. 2015, vol.7, n.1, pp.08-16. ISSN 2072-8174.  https://doi.org/10.18004/rdn2015.0007.01.008-016.

Introduction: dengue fever is an infection with multisystem involvement, self-limiting, clinical spectrum ranging from asymptomatic to severe and fatal forms. There are descriptions of cases of renal disease worldwide. Objective: to describe renal manifestations of dengue. Methodology: observational, descriptive, prospective study in adult patients with severe dengue admitted to the Department of Internal Medicine, National Hospital (Itauguá, Paraguay) during summer 2013 to 2013 epidemic. We evaluated clinical and laboratory parameters with emphasis on renal function. Results: 135 patients, 69 men and 66 women were recruited, mean age 42.7 ± 18 years. In 37% of cases there was any comorbidity. 24 h proteinuria were measured in 34 subjects, being in nephrotic range at 8.8% and high range (= 160 mg / day) in 67.6%. Other striking findings were hematuria (38%) and transient hypertension (39%). Only one patient presented alterations in urea and creatinine at discharge. Conclusions: renal manifestations of severe dengue are common, predominantly proteinuria, hematuria and hypertension, although they are transient in most.

Keywords : Dengue, Risk factors, Kidney, Hypertensión, Adults, Paraguay.

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