Abstract

CENTURION, Rosa; RIENZI, Rocio; GODOY, Gladys  and  BUENA, José. Perinatal dengue infection in a hospital in the central province of Paraguay. Rev. Nac. (Itauguá) [online]. 2014, vol.6, n.2, pp.38-54. ISSN 2072-8174.

Introduction: dengue infection during pregnancy can endanger the life of the mother and child; it is important to recognize it. Objectives: To identify clinical and epidemiological pregnant woman with diagnosis (dx) of dengue at the time of child birth. To describe the clinical characteristics and outcome of newborns (RN). Material and Methods: Case series of dengue RN mothers at birth and postpartum, during epidemics of the disease in the country in 2012 and 2013, admitted to the Neonatal Service of the National H.. The Dx of dengue in pregnant and RN considered taking into account the epidemiology, and / or serological confirmation (positive viremia determined by PCR and / or positive for dengue IgM capture Elisa). Results: 12 pregnant and 13 RN were included, with a pair of twins. Mothers came from the Central Department and neighboring cities.; were aged 18 years (15-34). Symptomatic were 10 (83.3%). 7 (58.3%) of them required hospitalization before birth. The symptoms occurred before birth in 6, the day of birth to 1, after birth in 1 and 2 the duration of symptoms was unknown. They underwent cesarean section 8 (66.6%); the reason of it was due to pre-eclampsia, eclampsia in 4 (50%), fetal distress 2 twin breech 1 and dengue in 1 case. 2 (16.6%) of the mothers died. Of the RN included 8 were female and 5 male; was considered to 9 RN with dx of dengue and dengue 4 without. The average EG in each group was 36.6 ± 1.4 and 37 ± 2 sem. respectively; birth weight of 2431 ± 381.9 and 3076.6 ± 899.1 gr. From 9 new born with dengue, 7 developed symptoms; 1 the day of birth and 6 after 24 hours and <7 days. The prominent symptoms were thrombocytopenia in 9; hemodynamic disorders, ascites and fever in 7; shortness of breath and pleural effusion in 4; abdominal distension 3; skin rash and eyelid edema in 2; hypoactivity, irritability, hypoglycemia and vomiting in one case each. 4 new born required transfusion of platelets. All were discharged alive with a duration of hospitalization of 16 ± 5.9 days.

Keywords : dengue; pregnant and newborn; vertical transmission.

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