Abstract

VERA, Lidia; MARTINEZ, Karina; KAIMEN, Florentina  and  SALDIVAR, Cecilia. Thyroid profile of outpatients attending at the Laboratory of the National Hospital. Rev. Nac. (Itauguá) [online]. 2012, vol.4, n.2, pp.35-40. ISSN 2072-8174.

ABSTRACT Introduction: the excess or deficiency of thyroid hormones can occur in all body systems, affecting multiple metabolic processes and influencing the concentration and activity of numerous enzymes, substrates metabolism, vitamins and minerals. Objectives: To evaluate thyroid profile of outpatients National Hospital (Itauguá) between December 2010 and May 2011, obtaining patient demographics and comorbidity estimates from altering laboratory values of TSH (thyroid stimulating hormone thyroid), T3 and FT4. Methodology: An observational, descriptive, cross-sectional, retrospective study, based on a review of 312 previously codified files that attended with a medical order for thyroid hormone evaluation at the National Hospital Laboratory (Itauguá). Results: we found that 34% (106/312) of the patients had thyroid profile disorders. The gender distribution obtained showed a higher prevalence of thyroid dysfunction in women 81%. The age range was mainly between 41-50 years. The majority of patients with thyroid disorders were from the Central Department (82%). The altered thyroid hormones values were: 32% primary hypothyroidism, secondary or tertiary hypothalamic-pituitary hypothyroidism 26%, 14% subclinical primary hypothyroidism, compensated primary hyperthyroidism 12%, primary hyperthyroidism 10% thyroid hormone resistance syndrome and pituitary TSH secreting tumors 6%. Conclusions: alteration of thyroid hormones occurred in 34% of the study population, mainly in women and the most relevant pathology is primary hypothyroidism.

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